Product Description: Targocil-II (Compound 2) is an ABC transporter inhibitor with a IC50 value of 137 nM. Targocil-II prevents ATP hydrolysis by binding to allosteric sites of the TM domain. Targocil-II has (antibacterial) activity[1].
Applications: COVID-19-immunoregulation
Formula: C26H22ClNO6
References: [1]Matano LM, et al. Antibiotic That Inhibits the ATPase Activity of an ATP-Binding Cassette Transporter by Binding to a Remote Extracellular Site. J Am Chem Soc. 2017 Aug 9;139(31):10597-10600.