TCO-PNB ester, CAS 1438415-89-4

Product Description: TCO-PNB ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. TCO-PNB ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

Applications: Cancer-programmed cell death

Formula: C15H17NO5

References: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

CAS Number: 1438415-89-4

Molecular Weight: 291.30

Compound Purity: 98.52

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: PROTAC Linkers

• SKU: MEXHY-141175-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-141175-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK