Product Description: TDI-11055 is an inhibitor of the epigenetic reader protein 11-19 leukemia (ENL) YEATS, which drives the oncogenic transcriptional program of acute myeloid leukemia (AML), the hematopoietic malignancy AML[1].
Formula: C22H24N6O
References: [1]Michino M, et al. Lead Optimization of Small Molecule ENL YEATS Inhibitors to Enable In Vivo Studies: Discovery of TDI-11055[J]. ACS Medicinal Chemistry Letters, 2024.
Molecular Weight: 388.47
Compound Purity: 99.43
Research Area: cancer
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Endogenous Metabolite