tert-Butyl 11-aminoundecanoate, CAS 220851-29-6

Product Description: tert-Butyl 11-aminoundecanoate (compound 6b) is a PROTAC linker, which refers to the PEG composition. tert-Butyl 11-aminoundecanoate can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Applications: Cancer-programmed cell death

Formula: C15H31NO2

References: [1]Kim K, et al. Disordered region of cereblon is required for efficient degradation by proteolysis-targeting chimera. Sci Rep. 2019 Dec 23;9(1):19654.

CAS Number: 220851-29-6

Molecular Weight: 257.41

Compound Purity: 99.36

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: PROTAC Linkers

• SKU: MEXHY-130715-1G
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-130715-1G
• Green Labware: No
• Package Unit: 1 g
• Quantity Unit: STK