TF-S14, CAS 2425563-60-4

Product Description: TF-S14 is a reverse agonist of RORγt (retinoic acid receptor-associated orphan receptor γt). TF-S14 reduces Th17 cell-associated cytokine production, including IL-17A, IL-21, and IL-22 by binding to and inhibiting RORγt activity. TF-S14 can be used in the study of autoimmune diseases and rejection in allotransplantation[1].

Formula: C22H27N3O2S

References: [1]Fouda A, et al. RORγt inverse agonist TF-S14 inhibits Th17 cytokines and prolongs skin allograft survival in sensitized mice[J]. Communications Biology, 2024, 7(1): 454.

CAS Number: 2425563-60-4

Molecular Weight: 397.53

Research Area: Others

Target: ROR

• SKU: MEXHY-162490-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162490-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK