TGF-β1/Smad3-IN-1

Product Description: TGF-β1/Smad3-IN-1 (Compound 5aa) is an inhibitor of the TGF-β1/Smad3 signaling pathway(IC50=1.07 μM). TGF-β1/Smad3-IN-1 possesses antifibrotic activity and oral potency[1].

Applications: COVID-19-immunoregulation

Formula: C30H34N4O6S

References: [1]An B, et al. Inhibition of TGF-β1/Smad3 signaling by compound 5aa: A potential treatment for idiopathic pulmonary fibrosis. Bioorg Chem. 2024 Apr 16;147:107374.

Molecular Weight: 578.68

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: TGF-beta/Smad

• SKU: MEXHY-163536-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163536-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK