Thalidomide-4-OH, CAS 5054-59-1

Product Description: Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs[1].

Applications: Cancer-programmed cell death

Formula: C13H10N2O5

References: [1]Marks MG, et al. Effects of putative hydroxylated thalidomide metabolites on blood vessel density in the chorioallantoic membrane (CAM) assay and on tumor and endothelial cell proliferation. Biol Pharm Bull. 2002 May;25(5):597-604.

CAS Number: 5054-59-1

Molecular Weight: 274.23

Compound Purity: 99.85

Research Area: Cancer

Solubility: DMSO : ≥ 36.5 mg/mL

Target: Apoptosis;Autophagy;E3 Ligase Ligand-Linker Conjugates

• SKU: MEXHY-103596-10G
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-103596-10G
• Green Labware: No
• Package Unit: 10 g
• Quantity Unit: STK