THK01, CAS 2226941-26-8

Product Description: THK01 is a potent ROCK2 inhibitor with IC50 values of 5.7 and 923 nM for ROCK2 and ROCK1, respectively. THK01 inhibits breast cancer metastasis through the ROCK2-STAT3 signaling pathway. THK01 can be used in research of breast cancer[1].

Formula: C20H13N3O2

References: [1]Wang J, et, al. Discovery of unglycosylated indolocarbazoles as ROCK2 isoform-selective inhibitors for the treatment of breast cancer metastasis. Eur J Med Chem. 2023 Mar 15;250:115181.

CAS Number: 2226941-26-8

Molecular Weight: 327.34

Compound Purity: 99.80

Research Area: Cancer

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: ROCK

• SKU: MEXHY-149266-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-149266-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK