Thymidine 5′-diphosphate (sodium), CAS 108322-12-9

Product Description: Thymidine 5′-diphosphate (dTDP) sodium is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate sodium is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg2+. Thymidine 5′-diphosphate sodium is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate[1][2].

Applications: COVID-19-immunoregulation

Formula: C10H16N2O11P2.xNa

References: [1]Cui Q, et al. Thymidylate kinase: an old topic brings new perspectives. Curr Med Chem. 2013;20(10):1286-305. /[2]Tzeng HF, et al. Simultaneous determination of thymidylate and thymidine diphosphate by capillary electrophoresis as a rapid monitoring tool for thymidine kinase and thymidylate kinase activities. Electrophoresis. 2005 Jun;26(11):2225-30.

CAS Number: 108322-12-9

Molecular Weight: N/A

Compound Purity: 98.0

Research Area: Infection

Solubility: H2O : 50 mg/mL (ultrasonic;warming)

Target: Endogenous Metabolite

• SKU: MEXHY-131576A-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-131576A-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK