TLR4-IN-C34-C2-amide-C6-OH

Product Description: TLR4-IN-C34-C2-amide-C6-OH is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis[1].

Applications: COVID-19-immunoregulation

Formula: C25H42N2O11

References: [1]Neal MD, et al. Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors. PLoS One. 2013;8(6):e65779. Published 2013 Jun 12.

Molecular Weight: 546.61

Compound Purity: 95.0

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: PROTAC Linkers;Toll-like Receptor (TLR)

• SKU: MEXHY-145245-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-145245-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK