Topovale, CAS 500214-53-9

Topovale, CAS 500214-53-9
SKU
MEXHY-118942-0
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MedChemExpress

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Product Description: Topovale (ARC 111) is a topoisomerase I inhbitor. Topovale is an antitumor agent, and shows low nM cytotoxicity against a panel of cancer cells. Topovale induces reversible topoisomerase I (TOP1) cleavage complexes in tumor cells[1].

Formula: C23H23N3O5

References: [1]Li TK, et al. Characterization of ARC-111 as a novel topoisomerase I-targeting anticancer drug. Cancer Res. 2003 Dec 1;63(23):8400-7.

CAS Number: 500214-53-9

Molecular Weight: 421.45

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Topoisomerase
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SKU MEXHY-118942-0
Manufacturer MedChemExpress
Manufacturer SKU HY-118942-0
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