Tos-PEG2-O-Propargyl, CAS 1119249-30-7

Product Description: Tos-PEG2-O-Propargyl is a PEG-based PROTAC linker can be used in the synthesis of Thalidomide-O-PEG2-propargyl (HY-126458)[1]. Tos-PEG2-O-Propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C14H18O5S

References: [1]Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461.

CAS Number: 1119249-30-7

Molecular Weight: 298.35

Compound Purity: 98.47

Research Area: Cancer

Solubility: Ethanol : 50 mg/mL (ultrasonic)

Target: PROTAC Linkers

• SKU: MEXHY-130162-1G
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-130162-1G
• Green Labware: No
• Package Unit: 1 g
• Quantity Unit: STK