TP-238 (hydrochloride), CAS 2415263-05-5

Product Description: TP-238 hydrochloride is a potent and selective dual CECR2/BPTF probe with IC50 values of 30 nM and 350 nM, respectively. TP-238 hydrochloride also inhibits BRD9 with a pIC50 of 5.9 and is less active against other 338 kinases[1][2].

Applications: Cancer-Kinase/protease

Formula: C22H31ClN6O3S

References: [1]Michael A Clegg, et al. Advancements in the Development of non-BET Bromodomain Chemical Probes. ChemMedChem. 2019 Feb 19;14(4):362-385./[2]Peter D Ycas, et al. New Inhibitors for the BPTF Bromodomain Enabled by Structural Biology and Biophysical Assay Development. Org Biomol Chem. 2020 Jun 26.

CAS Number: 2415263-05-5

Molecular Weight: 495.04

Compound Purity: 99.0

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Epigenetic Reader Domain

• SKU: MEXHY-114205A-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-114205A-100
• Green Labware: No
• Package Unit: 100 mg
• Quantity Unit: STK