Product Description: TPA-dT is a thymidine analog with a tris[(2-pyridyl)methyl]amine (TPA) group. TPA-dT can be used to modify siRNAs. The TPA-modified siRNAs remain functionally inactive and is incapable of silencing gene expression until the TPA moiety is removed upon exposure to Cu(I)[1].
Formula: C29H32N6O5
References: [1]Morihiro K, et al. Copper-mediated siRNA activation for conditional control of gene expression. Bioorg Med Chem Lett. 2024 May 15;104:129738.