Trilexium, CAS 1983180-82-0

Product Description: Trilexium (TRX-E-009-1) is a third-generation of benzopyran structurally related to TRX-E-002-1 (HY-114250). Trilexium increases p21 protein expression and induces apoptosis. Trilexium depolymerizes microtubules. Trilexium shows broad anti-cancer activity[1][2].

Formula: C24H23FO6

References: [1]Stevenson AJ, et al. Mechanism of action of the third generation benzopyrans and evaluation of their broad anti-cancer activity in vitro and in vivo. Sci Rep. 2018 Mar 23;8(1):5144. /[2]Ehteda A, et al. Microtubule-Targeting Combined with HDAC Inhibition Is a Novel Therapeutic Strategy for Diffuse Intrinsic Pontine Gliomas. Mol Cancer Ther. 2023 Dec 1;22(12):1413-1421.

CAS Number: 1983180-82-0

Molecular Weight: 426.43

Compound Purity: 99.70

Research Area: Cancer

Solubility: DMSO : 300 mg/mL (ultrasonic)

Target: Apoptosis;Caspase;Microtubule/Tubulin;PARP

• SKU: MEXHY-157800-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-157800-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK