TrxR1-IN-B19, CAS 170950-29-5

Product Description: TrxR1-IN-B19 (GO-Y015) (Compound B19) is a Curcumin (HY-N0005) derivative and colvalent TrxR1 inhibitor. TrxR1-IN-B19 inhibits TrxR1 enzyme activity to elevate oxidative stress, and then induce ROS-mediated ER Stress and mitochondrial dysfunction, subsequently resulting in cell cycle arrest and apoptosis[1].

Formula: C21H22O5

References: [1]Chen W,et al. Selective killing of gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stress activation. Oncotarget. 2016 Mar 29;7(13):16593-609.

CAS Number: 170950-29-5

Molecular Weight: 354.40

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;TrxR

• SKU: MEXHY-120914-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-120914-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK