Product Description: TS-24 is an inhibitor for cathepsin S, with an IC50 of 4.3 μM. TS-24 exhibits radiosensitizing activity in wild type breast cancer susceptibility gene 1 (BRCA1) and in TNBC xenograft mice model, through induction of apoptosis[1].
Formula: C20H15NO2
References: [1]Choi E, et al., Radiosensitizing effect of a novel CTSS inhibitor by enhancing BRCA1 protein stability in triple-negative breast cancer cells. Cancer Sci. 2024 Apr 13.
CAS Number: 1563260-97-8
Molecular Weight: 301.34
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Apoptosis;Cathepsin