Product Description: TT01001 is a potent and orally active mitoNEET ligand. TT01001 reduces oxidative stress injury and neuronal apoptosis by improving mitochondrial dysfunction. TT01001 improves type II diabetes without causing weight gain[1][2].
Applications: Metabolism-sugar/lipid metabolism
Formula: C15H19Cl2N3O2S
References: [1]Takehiro Takahashi, et al. A novel MitoNEET ligand, TT01001, improves diabetes and ameliorates mitochondrial function in db/db mice. J Pharmacol Exp Ther. 2015, 352, 2./[2]Shi G, et al. TT01001 attenuates oxidative stress and neuronal apoptosis by preventing mitoNEET-mediated mitochondrial dysfunction after subarachnoid hemorrhage in rats. Neuroreport. 2020;31(11):845-850.
CAS Number: 1022367-69-6
Molecular Weight: 376.30
Compound Purity: 99.38
Research Area: Metabolic Disease; Neurological Disease
Solubility: DMSO : 125 mg/mL (ultrasonic)
Target: Apoptosis;Mitochondrial Metabolism;Reactive Oxygen Species