Product Description: Tubulin inhibitor 44 (Compound 26r) is an inhibitor for tubullin. Tubulin inhibitor 44 exhibits cytotoxicity in cancer cells NCI-H460, BxPC-3 and HT-29, with IC50s of 0.96, 0.66 and 0.61 nM, respectively[1].
Formula: C28H24FN3O4
References: [1]Wang S, et al., Design, synthesis, and structure-activity relationship study of novel plinabulin derivatives as anti-tumor agents based on the co-crystal structure. Mol Divers. 2024 Apr 23.
CAS Number: 3025180-36-0
Molecular Weight: 485.51
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Microtubule/Tubulin