Tubulin polymerization-IN-43, CAS 2773345-90-5

Product Description: Tubulin polymerization-IN-43 (compound 15h) is a tubulin polymerization inhibitor. Tubulin polymerization-IN-43 disrupts cellular microtubule networks by targeting the Colchicine (HY-16569) site, and promots cell cycle arrest of leukemia cells at G2/M phase and cell apoptosis, as well as inhibiting angiogenesis[1].

Formula: C17H13F4N3O

References: [1]Wu H, et, al. Discovery of novel N-aryl-2-trifluoromethyl-quinazoline-4-amine derivatives as the inhibitors of tubulin polymerization in leukemia cells. Eur J Med Chem. 2023 Aug 5;256:115470.

CAS Number: 2773345-90-5

Molecular Weight: 351.30

Compound Purity: 99.60

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Microtubule/Tubulin

• SKU: MEXHY-149363-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-149363-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK