Product Description: UM4118 is a copper ionophore that can initiate a mitochondrial-based noncanonical form of cell death known as cuproptosis. UM4118 exhibits high sensitivity in SF3B1-mutated and adverse risk acute myeloid leukemia (AML), and can be used for AML research[1].
Formula: C15H11N3O
References: [1]Moison C, et al. <i>SF3B1</i> mutations provide genetic vulnerability to copper ionophores in human acute myeloid leukemia. Sci Adv. 2024;10(12):eadl4018.