UNC8969

Product Description: UNC8969 (compound 43) is a MERTK/AXL dual inhibitor with IC50s of 1.1±0.8 nM for MERTK and 5.3 ± 2.7 nM for AXL. UNC8969 also exerts a T1/2 of 7.3 h with 5 mg/kg i.v. in mice[1].

Formula: C29H41N7O3

References: [1]Discovery of Novel Macrocyclic MERTK/AXL Dual Inhibitors. J Med Chem. 2024 Apr 11;67(7):5866-5882.

Molecular Weight: 535.68

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Others

• SKU: MEXHY-162406-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162406-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK