URAT1/GLUT9-IN-1, CAS 2883011-18-3

URAT1/GLUT9-IN-1, CAS 2883011-18-3
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MEXHY-158056-0
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Product Description: URAT1/GLUT9-IN-1(compound 29) can inhibit both uric acid transporter 1(URAT1)(IC50=2.01 μM) and glucose transporter 9(GLUT9)(IC50=18.21 μM). URAT1/GLUT9-IN-1 exhibits favorable pharmacokinetic properties and oral bioavailability. URAT1/GLUT9-IN-1 can be uesd for gout and hyperuricemia research[1].

Formula: C23H21N3O2S2

References: [1]Shi X, et al. Discovery of a Novel Thienopyrimidine Compound as a Urate Transporter 1 and Glucose Transporter 9 Dual Inhibitor with Improved Efficacy and Favorable Druggability[J]. Journal of Medicinal Chemistry, 2024, 67(6): 5032-5052.

CAS Number: 2883011-18-3

Molecular Weight: 435.56

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: GLUT;URAT1
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SKU MEXHY-158056-0
Manufacturer MedChemExpress
Manufacturer SKU HY-158056-0
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