Product Description: Uridine diphosphate glucuronic acid (UDP-α-D-glucuronic acid) is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum[1][2].
Applications: Metabolism-sugar/lipid metabolism
Formula: C15H22N2O18P2
References: [1]Annika J E Borg, et al. Mechanistic characterization of UDP-glucuronic acid 4-epimerase. FEBS J. 2021 Feb;288(4):1163-1178./[2]DUTTON GJ. Uridine diphosphate glucuronic acid as glucuronyl donor in the synthesis of ester, aliphatic and steroid glucuronides. Biochem J. 1956 Dec;64(4):693-701.
CAS Number: 2616-64-0
Molecular Weight: 580.29
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: Endogenous Metabolite