Venetoclax, CAS 1257044-40-8

Description: Venetoclax (ABT-199) is a Bcl-2 inhibitor (Ki<0.01 nM) with potent, selective, and orally active properties. Venetoclax has a 3-order-of-magnitude lower affinity for Bcl-xL and Bcl-W (Kis=48/245 nM). Venetoclax induces autophagy and apoptosis.

CAS Number: 1257044-40-8

Formula: C45H50ClN7O7S

Molecular Weight: 868,44

References: Peirs S, et al. ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia. Blood. 2014 Dec 11;124(25):3738-47.

• SKU: TGMT2119-1mL
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T2119-1mL
• Package Unit: 1 mL
• Quantity Unit: STK