VHL Ligand 14, CAS 2010986-87-3

Product Description: VHL Ligand 14 (Compound 11) is a VHL ligand for design of PROTAC estrogen receptor α (ERα) degraders, with a binding affinity IC50 of 196 nM[1].

Formula: C25H34N4O4S

References: [1]Hu J, et al., Discovery of ERD-308 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Estrogen Receptor (ER). J Med Chem. 2019 Feb 14;62(3):1420-1442.

CAS Number: 2010986-87-3

Molecular Weight: 486.63

Compound Purity: 99.93

Research Area: Cancer

Solubility: DMSO : ≥ 100 mg/mL

Target: Ligands for E3 Ligase

• SKU: MEXHY-150803-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-150803-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK