VPM-p15

Product Description: Vmm-p15 is a peptide agonist optimized for the adhesion G protein-coupled receptor GPR64 (also known as ADGRG2 or HE6). The affinity of VPM-p15 with GPR64 is significantly higher than that of the original p15 peptide. The cAMP level induced by VMM-P15 increased significantly, activated GPR64, and triggered downstream Gs, Gq, and G12/13 signaling. VPM-p15 can be used to study the activation mechanism of adherent GPCR family members[1].

Formula: C75H126N18O22

References: [1]Sun Y, et al. Optimization of a peptide ligand for the adhesion GPCR ADGRG2 provides a potent tool to explore receptor biology[J]. Journal of Biological Chemistry, 2021, 296.

Molecular Weight: 1631.91

Research Area: Others

Solubility: 10 mM in DMSO

Target: Others

• SKU: MEXHY-P10365-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P10365-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK