WD6305 (TFA)

Product Description: WD6305 TFA is a potent METTL3-targeted PROTAC degrader. WD6305 TFA selectively reduces the METTL3 and METTL14 complex. WD6305 TFA inhibits m6A modification and the proliferation of AML cells and promotes apoptosis. WD6305 TFA can be used for the research of leukemic[1].

Formula: C63H76F5N11O7S

References: [1]Du W, et al. Discovery of a PROTAC degrader for METTL3-METTL14 complex. Cell Chem Biol. 2024 Jan 2:S2451-9456(23)00439-7

Molecular Weight: 1226.40

Compound Purity: 98.47

Research Area: Cancer

Solubility: DMSO : 95 mg/mL (ultrasonic)

Target: Apoptosis;PROTACs

• SKU: MEXHY-160415A-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-160415A-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK