Product Description: WL 47 dimer (ligand 1) is a caveolin-1 (CAV-1) ligand with high affinity, selectivity and oligomer dissociation activity. WL 47 dimer simultaneously occupies two binding sites of CAV-1, inducing the dissociation of oligomers. WL 47 dimer has 7500-fold improved affinity compared to its T20 parent ligand and an 80% decrease in sequence length. WL 47 dimer can be used to permit targeted study of CAV-1 function[1].
Formula: C80H130N24O18S4
References: [1]Gilliam A J H, et al. Affinity-guided design of caveolin-1 ligands for deoligomerization[J]. Journal of medicinal chemistry, 2016, 59(8): 4019-4025.
Molecular Weight: 1844.30
Research Area: Others
Solubility: 10 mM in DMSO
Target: Others