Wortmannin, CAS 19545-26-7

Description: Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible. Wortmannin is also an inhibitor of PlK1 and PlK3 (IC50=5.8/48 nM) that blocks autophagy.

CAS Number: 19545-26-7

Formula: C23H24O8

Molecular Weight: 428,43

References: Akter R, et al. Wortmannin induces MCF-7 breast cancer cell death via the apoptotic pathway, involving chromatin condensation, generation of reactive oxygen species, and membrane blebbing. Breast Cancer (Dove Med Press). 2012 Jul 13;4:103-13.

• SKU: TGMT6283-5mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T6283-5mg
• Package Unit: 5 mg
• Quantity Unit: STK