WRN inhibitor 7, CAS 444780-45-4

Product Description: WRN inhibitor 7 (Compound h6) is a WRN inhibitor. WRN inhibitor 7 effectively inhibits WRN's helicase and ATPase activity (IC50: 9.8 μM and 15.8 μM respectively). WRN inhibitor 7 can be used for research of microsatellite instable (MSI) cancers[1].

Formula: C27H23N3O6

References: [1]Yuan H, et al. Targeting ATP-binding site of WRN Helicase: Identification of novel inhibitors through pocket analysis and Molecular Dynamics-Enhanced virtual screening. Bioorg Med Chem Lett. 2024 May 15;104:129711.

CAS Number: 444780-45-4

Molecular Weight: 485.49

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: DNA/RNA Synthesis

• SKU: MEXHY-161386-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-161386-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK