YAP-TEAD-IN-3, CAS 2714434-21-4

Product Description: YAP-TEAD-IN-3 (compound 155) is a YAP/TAZ-TEAD inhibitor. YAP-TEAD-IN-3 inhibits Avi-humanTEAD4217-434 with an IC50 value of 9 nM. YAP-TEAD-IN-3 also inhibits NCI-H2052 with an GI50 of 0.048 μM (cell proliferation)，and an IC50 of 0.048 μM (YAP reporter gene expression)，respsectively[1].

Applications: Cancer-programmed cell death

Formula: C27H26ClF2N3O4

References: [1]Bordas V, et al. Preparation of biaryl derivatives as YAP/TAZ-TEAD protein-protein interaction inhibitors. World Intellectual Property Organization, WO2021186324 A1. 2021-09-23.

CAS Number: 2714434-21-4

Molecular Weight: 529.96

Compound Purity: 99.81

Research Area: Cancer

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: YAP

• SKU: MEXHY-153811-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-153811-100
• Green Labware: No
• Package Unit: 100 mg
• Quantity Unit: STK