Product Description: YCH2823 is an inhibitor of USP7 (IC50 = 49.6 nM; Kd = 0.117 μM). YCH2823 shows significant efficacy in inhibiting TP53 wild-type and mutant tumors, with approximately 5-fold higher potency than FT671. YCH2823 induce apoptosis. YCH2823 synergistic effects with mTOR inhibitors[1].
Applications: Cancer-programmed cell death
Formula: C29H32N4O4
References: [1]Yong-Jun C et al. Identification of YCH2823 as a novel USP7 inhibitor for cancer therapy Elsevier Inc.. 2024 Apr 116071.