Z-IETD-R110

Product Description: Z-IETD-R110 is a fluorescent substrate of caspases. Z-IETD-R110 acts as a substrate for caspase-8. When caspase-8 is activated, it can recognize and cut Z-IETD-R110, releasing fluorophore, which can be detected by fluorescence microscopy. Z-IETD-R110 can be used to study oxidative stress-induced apoptosis, particularly in pancreatic acinar cells[1].

Applications: COVID-19-immunoregulation

Formula: C74H86N10O25

References: [1]Baumgartner H K, et al. Caspase-8-mediated apoptosis induced by oxidative stress is independent of the intrinsic pathway and dependent on cathepsins[J]. American Journal of Physiology-Gastrointestinal and Liver Physiology, 2007, 293(1): G296-G307.

Molecular Weight: 1515.53

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Fluorescent Dye

• SKU: MEXHY-P10322-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P10322-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK