(Z)-JQ1-TCO

Product Description: JQ1-TCO (JQ1-trans-cyclooctene) is a derivative of JQ1 (HY-13030), an inhibitor of BET. JQ1-TCO is suitable for click chemistry and can be used as molecular probes in vitro and in vivo[1][2].

Formula: C31H37ClN6O3S

References: [1]Hu Z, et al. Recent Developments in PROTAC-Mediated Protein Degradation: From Bench to Clinic. Chembiochem. 2022 Jan 19;23(2):e202100270. /[2]Tyler DS, et al. Click chemistry enables preclinical evaluation of targeted epigenetic therapies. Science. 2017 Jun 30;356(6345):1397-1401.

Molecular Weight: 609.18

Compound Purity: 99.34

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Epigenetic Reader Domain

• SKU: MEXHY-148864A-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-148864A-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK