p38α MAPK-IN-1, CAS 443913-15-3

Formulation: A solid

Formal Name: N-[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N′-[4-[2-(4-morpholinyl)ethoxy]phenyl]-urea

Purity: ≥98%

Formula Markup: C27H35N5O3

Formula Weight: 477,6

Shelf life (days): 1460

CAS Number: 443913-15-3

Notes: p38α MAPK-IN-1 is an inhibitor of p38α MAPK (IC50 = 5,500 nM in a homogeneous time-resolved fluorescence (HTRF) assay).{66779} It inhibits TNF-α production induced by LPS in THP-1 cells (EC50 = 6,200 nM).{66780} p38α MAPK-IN-1 has been used in the study of p38α MAPK inhibitor binding interactions and kinetics.{66779,66780}

• SKU: CAY40839-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 40839-50
• Package Unit: 50 mg
• Quantity Unit: STK