PFI-653, CAS 2173134-00-2

Formulation: A solid

Formal Name: 8-oxa-2-azaspiro[4.5]dec-2-yl[2-[(2-pyrazinylmethyl)amino]-5-pyrimidinyl]-methanone

Purity: ≥98%

Formula Markup: C18H22N6O2

Formula Weight: 354,4

Shelf life (days): 1460

CAS Number: 2173134-00-2

Notes: PFI-653 is an inhibitor of the pantetheinase vanin-1 (IC50 = 6.85 nM for the human enzyme).{67779} In vivo, PFI-653 (50 mg/kg) prevents reductions in body weight, as well as reduces disease severity and serum vanin-1 levels in a mouse model of colitis induced by dextran sulfate sodium (DSS; Item No. 23250). See the Structural Genomics Consortium (SGC) website for more information.

• SKU: CAY40955-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 40955-10
• Package Unit: 10 mg
• Quantity Unit: STK