Formulation: A solid
Formal Name: α-oxo-benzenepropanoic acid
Purity: ≥95%
Formula Markup: C9H8O3
Formula Weight: 164,2
Shelf life (days): 1460
CAS Number: 156-06-9
Notes: Phenylpyruvic acid is an active metabolite of the essential amino acid L-phenylalanine (Item No. 31498) and a biosynthetic precursor to the antifungal phenyl alkanoic acid 3-phenyllactic acid (Item No. 36365).{66476,66477} It inhibits glucose-6-phosphate dehydrogenase (G6PDH) in rat brain homogenates when used at concentrations of 0.6 and 1.2 mM.{66476} Addition of phenylpyruvic acid to the culture medium of lactic acid bacteria increases 3-phenyllactic acid levels in, and the antifungal activity of, the cell-free culture supernatant.{66477} Urinary levels of phenylpyruvic acid are increased in patients with phenylketonuria (PKU), an inborn error of metabolism characterized by a deficiency in phenylalanine hydroxylase (PAH) activity.{66478}
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