2-Amino-2-(p-tolyl)acetic acid, CAS 13227-01-5

Product Description: 2-Amino-2-(p-tolyl)acetic acid is used for optimizing azide skeleton, and is the intermediate in the synthesis of 1,3, 4-thiadiazole compounds. 1,3,4-thiadiazole compounds exhibit potential anti-cancer activity, and inhibit glutaminase (GLSI)[1][2].

Applications: Cancer-programmed cell death

Formula: C9H11NO2

References: [1]Kalie A M, et al. Cytosolic Delivery of Proteins by Bioreversible Esterification. JAmChem. 2017. 139(41):14396–14398./[2]Finlay MRV, et al. Preparation of 1,3,4-thiadiazole compounds and their use in treating cancer: World Intellectual Property Organization, WO2017093301[P]. 2017-06-08.

CAS Number: 13227-01-5

Molecular Weight: 165.19

Compound Purity: 97.0

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)/H2O : 1 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Glutaminase

• SKU: MEXHY-W006187-1G
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W006187-1G
• Green Labware: No
• Package Unit: 1 g
• Quantity Unit: STK