α-Helical CRF(9-41), CAS 90880-23-2

Product Description: α-Helical CRF(9-41) is a competitive CRF2 receptor antagonist with KB of ~100 nM. α-Helical CRF(9-41) is also a partial agonist of CRF1 receptor with an EC50 of 140 nM[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C166H274N46O53S2

References: [1]Sonia Tucci, et al. Corticotropin releasing factor antagonist, alpha-helical CRF(9-41), reverses nicotine-induced conditioned, but not unconditioned, anxiety. Psychopharmacology (Berl). 2003 May;167(3):251-6./[2]Smart D, et al. Characterisation using microphysiometry of CRF receptor pharmacology. Eur J Pharmacol. 1999 Aug 27;379(2-3):229-35.

CAS Number: 90880-23-2

Molecular Weight: 3826.40

Compound Purity: 99.74

Research Area: Neurological Disease

Solubility: H2O : 50 mg/mL (ultrasonic)

Target: CRFR

• SKU: MEXHY-P1294-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P1294-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK