AC-264613, CAS 1051487-82-1

Product Description: AC-264613 is a potent and selective protease-activated receptor (PAR-2) agonist with a pEC50 of 7.5[1].

Applications: COVID-19-immunoregulation

Formula: C19H18BrN3O2

References: [1]Jimmi Gerner Seitzberg, et al. Discovery of potent and selective small-molecule PAR-2 agonists. J Med Chem. 2008 Sep 25;51(18):5490-3./[2]Rui Yamaguchi, et al. A protease-activated receptor 2 agonist (AC-264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macrophages: Role of p53. Cell Biol Int. 2016 Jun;40(6):629-41./[3]Luis R Gardell, et al. Identification and characterization of novel small-molecule protease-activated receptor 2 agonists. J Pharmacol Exp Ther. 2008 Dec;327(3):799-808.

CAS Number: 1051487-82-1

Molecular Weight: 400.27

Compound Purity: 98.3

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Protease Activated Receptor (PAR)

• SKU: MEXHY-14351-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-14351-5
• Package Unit: 5 mg
• Quantity Unit: STK