ADT-007, CAS 1945941-09-2

Product Description: ADT-007 is a potent and orally active pan-RAS inhibitor with strong anticancer effects. ADT-007 binds RAS in a nucleotide-free conformation to block GTP activation. ADT-007 potently and selectively inhibits the growth of cancer cells with mutated or hyper-activated wild-type RAS isozymes[1].

Applications: Cancer-Kinase/protease

Formula: C26H24FNO5

References: [1]Jeremy B Foote, et al. A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI Cancer. bioRxiv[Preprint]. 2024 Jan 24:2023.05.17.541233.

CAS Number: 1945941-09-2

Molecular Weight: 449.47

Compound Purity: 99.97

Research Area: Cancer

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: Ras

• SKU: MEXHY-157887-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-157887-10.1
• Package Unit: 10mM/1mL
• Quantity Unit: STK