Allitinib, CAS 897383-62-9

Product Description: Allitinib (AST-1306) is an orally active and irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. Allitinib also inhibits ErbB4 with an IC50 of 0.8 nM. Allitinib is an anilino-quinazoline compound and has anti-cancer activity[1].

Applications: Cancer-Kinase/protease

Formula: C24H18ClFN4O2

References: [1]Xie H, Lin L, Tong L et al. AST1306, a novel irreversible inhibitor of the epidermal growth factor receptor 1 and 2, exhibits antitumor activity both in vitro and in vivo. PLoS One. 2011;6(7):e21487.

CAS Number: 897383-62-9

Molecular Weight: 448.88

Compound Purity: 99.36

Research Area: Cancer

Solubility: DMSO : 20 mg/mL (ultrasonic;warming;heat to 60°C)

Target: EGFR

• SKU: MEXHY-15375-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-15375-5
• Package Unit: 5 mg
• Quantity Unit: STK