Product Description: Angiopoietin 4 protein (ANGPT4) critically binds to TEK/TIE2, regulates ANGPT1 signaling and induces TEK/TIE2 phosphorylation. In addition to regulation, ANGPT4 promotes endothelial cell survival, migration, and angiogenesis. Angiopoietin-4 Protein, Human (HEK293, Fc) is the recombinant human-derived Angiopoietin-4 protein, expressed by HEK293 , with N-hFc labeled tag.
Formula: 51378(Gene_ID)Q9Y264-1 (M282-I503)(Accession)
References: [1]Dittrich GM, et al. Fibroblast GATA-4 and GATA-6 promote myocardial adaptation to pressure overload by enhancing cardiac angiogenesis. Basic Res Cardiol. 2021 Apr 19;116(1):26./[2]Wu Z, et al. Single-cell analysis reveals an Angpt4-initiated EPDC-EC-CM cellular coordination cascade during heart regeneration. Protein Cell. 2023 May 8;14(5):350-368.
Molecular Weight: Approximately 58-77 kDa due to the glycosylation.
Compound Purity: 91.40
English
Deutsch
