Apricoxib, CAS 197904-84-0

Apricoxib, CAS 197904-84-0
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MEXHY-14783-0
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MedChemExpress

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Product Description: Apricoxib (CS 706) is a selective inhibitor for cyclooxygenase-2 (COX-2). Apricoxib inhibits the production of PGE2 in cells with IC50 of 1.5 nM. Apricoxib exhibits anticancer, analgesic and anti-inflammatory activities[1].

Formula: C19H20N2O3S

References: [1]Reckamp K, et al., Biomarker-based phase I dose-escalation, pharmacokinetic, and pharmacodynamic study of oral apricoxib in combination with erlotinib in advanced nonsmall cell lung cancer. Cancer. 2011 Feb 15;117(4):809-18.

CAS Number: 197904-84-0

Molecular Weight: 356.44

Research Area: Cancer; Inflammation/Immunology; Neurological Disease

Target: COX;Prostaglandin Receptor
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SKU MEXHY-14783-0
Manufacturer MedChemExpress
Manufacturer SKU HY-14783-0
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