Product Description: Apricoxib (CS 706) is a selective inhibitor for cyclooxygenase-2 (COX-2). Apricoxib inhibits the production of PGE2 in cells with IC50 of 1.5 nM. Apricoxib exhibits anticancer, analgesic and anti-inflammatory activities[1].
Formula: C19H20N2O3S
References: [1]Reckamp K, et al., Biomarker-based phase I dose-escalation, pharmacokinetic, and pharmacodynamic study of oral apricoxib in combination with erlotinib in advanced nonsmall cell lung cancer. Cancer. 2011 Feb 15;117(4):809-18.
CAS Number: 197904-84-0
Molecular Weight: 356.44
Research Area: Cancer; Inflammation/Immunology; Neurological Disease
Target: COX;Prostaglandin Receptor