AXL-IN-13, CAS 2376928-82-2

Product Description: AXL-IN-13 is a potent and orally active AXL inhibitor (IC50: 1.6 nM, Kd: 0.26 nM). AXL-IN-13 reverses TGF-β1-induced epithelial-mesenchymal transition (EMT), and inhibits cancer cell migration and invasion[1].

Applications: Cancer-Kinase/protease

Formula: C34H41FN6O5

References: [1]Chan S, et al. Discovery of 3-Aminopyrazole Derivatives as New Potent and Orally Bioavailable AXL Inhibitors. J Med Chem. 2022 Nov 24;65(22):15374-15390.

CAS Number: 2376928-82-2

Molecular Weight: 632.72

Compound Purity: 98.03

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: FLT3;PDGFR;TAM Receptor

• SKU: MEXHY-151904-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-151904-10.1
• Package Unit: 10mM/1mL
• Quantity Unit: STK