AY254, CAS 2093408-03-6

Product Description: AY254 is an analogue of AY77 (HY-138951). AY254 is ERK-biased PAR2 agonist with an EC50 of 2 nM. AY254 relieves cytokine-induced caspase 3/8 activation. AY254 also promotes scratch-wound healing and induced IL-8 secretion via PAR2-ERK1/2 signaling[1]

Applications: COVID-19-immunoregulation

Formula: C30H49N9O6

References: [1]Jiang Y, et al. Biased Signaling by Agonists of Protease Activated Receptor 2. ACS Chem Biol. 2017 May 19;12(5):1217-1226.

CAS Number: 2093408-03-6

Molecular Weight: 631.77

Research Area: Cancer; Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Protease Activated Receptor (PAR)

• SKU: MEXHY-P3259-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P3259-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK