Product Description: AZD2098 is a potent and selective CC-chemokine receptor 4 (CCR4) inhibitor with pIC50s of 7.8, 8.0, 8.0 and 7.6 for human, rat, mouse and dog respectively, used for asthma research[1][2].
Applications: COVID-19-immunoregulation
Formula: C11H9Cl2N3O3S
References: [1]Kindon N, et al. Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists. ACS Med Chem Lett. 2017 Sep 1;8(9):981-986./[2]Asher Mullard. Cancer charity sees success re-prioritizing industry's shelved compounds. Nat Rev Drug Discov. 2014 May;13(5):319-21.
CAS Number: 566203-88-1
Molecular Weight: 334.18
Compound Purity: 99.84
Research Area: Inflammation/Immunology; Endocrinology
Solubility: DMSO : 100 mg/mL (ultrasonic)/Ethanol : 5 mg/mL (ultrasonic;warming;heat to 60°C)
Target: CCR