Product Description: B4148 is a selective competitive bradykinin (BK) antagonist that significantly inhibits BK-induced hypotension in rats. In a rat model of endotoxin shock induced by Escherichia coli lipopolysaccharide, B4148 significantly attenuated the decrease in mean arterial blood pressure compared with the control group[1].
Applications: Neuroscience-Neuromodulation
Formula: C62H95N19O14S2
References: [1]Endotoxin shock in the rat: reduction of arterial blood pressure fall by the bradykinin antagonist B4148.