Product Description: BCR-ABL1-IN-1 is a potent, orally active, and specific inhibitor of ABL kinase. BCR-ABL1-IN-1 has potential for elucidating the role of ABL kinases in the brain in non-clinical studies[1].
Applications: Neuroscience-Neuromodulation
Formula: C18H12F3N3O2
References: [1] Manley PW, et al. A kinase inhibitor which specifically targets the ABL myristate pocket (STAMP), but unlike asciminib crosses the blood-brain barrier. Bioorg Med Chem Lett. 2022;59:128577.
CAS Number: 1488090-21-6
Molecular Weight: 359.30
Compound Purity: 99.82
Research Area: Neurological Disease
Solubility: DMSO : 175 mg/mL (ultrasonic)
Target: Bcr-Abl